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Long-term side effects of rybelsus are still being studied, but current data shows the medication is generally well-tolerated with continued use

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Figure 6 Our observations implied that MAPKAPK2 was associated with reduced KEAP1 levels and enhanced Nrf2 nuclear localization, concomitant with increased HO-1 expression, suggesting a potential role in reinforcing antioxidant defenses in vitiligo melanocytes